A comparative study of blood cells variations and serum factors between children with Giardia lamblia and that of control group

FatemehTabatabaie, Narges Shah

Abstract

Giardiasis is an infection caused by flagellated protozoan which is called Giardia lamblia. The protozoa is an intestinal parasite and has a global distribution.The prevalence of it varies between 5% -30%.The present study was undertaken to analyze probable correlation between blood cells and immune system status in children aged 2 to 10 years with giardiasis who selected from Iran University of Medical Sciences hospitals. Children with giardiasis underwent precise laboratory analysis with regard to blood cell counts (lymphocytes, monocytes and polymorph nuclear cells) and serum factors (Immunoglobulin and complements components).The examination showed that the blood in affected children with giardiasis has a significant reduction in terms of lymphocytes and monocytes.Whilst otherwise, white cells showed no significant differences. Similarly, serum analysis defined significant reduction in C3 and C4 complements components. In contrast, despite observing insignificant differences in amount of IgG, serum level of IgE, IgM and IgA immunoglobulin increased significantly. These differences are possibly related to cellular immune function and complement system.