A convenient synthesis of azlactone derivatives catalyzed by scolecite zeolite

L.S.Gadekar, R.G.Machale

Abstract

Asimple and efficient procedure for the synthesis of 4-Arylidene-2-phenyl- 5(4)-oxazolones (Azlactone) derivatives through the condensation of aromatic aldehydes and hippuric acid in acetic unhydride medium at 70°C is described. The reaction goes smoothly. Simple experimental procedure, easy work- up and good yield of the products are the advantages of the present work.

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