A Mini Review on My Study of the Spinal Cord Injury

Mini Review

Gong Ju


Spinal cord contusion was an injury that had never been effectively treated. The general pathology of the spinal cord contusion had long been studied and published. The major point is that after spinal cord contusion there develops a secondary injury with a necrotic center, which induces gradual expansion of the injury. The logical treatment should be debridment of the necrotic center to terminate further expansion. An early neurosurgery of the spinal cord contusion was designed and practiced clinically. Basically, MRI to determine the level of spinal cord contusion, make a longitudinal incision of the dura mater to expose the injured part of spinal cord. Debride ts necrotic tissue. The operation was followed by intensive rehabilitation for three months. Thirty ASIA-A grade patients were admitted. All the patients resumed certain degree of walk ability. The best result occurred in 13 patients operated 4-14 days after injury (the optimal operation time window). Eleven of the 13 cases were able to walk with a pair of crutches or even to walk without any support. A laboratory of cellular and molecular biology was established to study the mechanism of spinal cord injury. It has an SPF laboratory for making transgenic/knock-out mice, and SPF animal housing rooms with a maximum capacity of 8,000 mice. In all, 103 SCI articles on spinal cord injury have been published.

Relevant Publications in Journal of Spine