A One-Pot Microwave Irradiation Synthesis of 1,2,4-Triazolo [1,5-A] Pyrimidines

Mahendra Borisagar, Kaushik Jo

Abstract

Synthesis of a series of triazolopyrimidines (4a-j) was achieved from different acetoacetamides, 4-(phenoxymethyl) benzaldehyde and 5-amino-1,2,4-triazole using microwave irradiation within 20-30 minutes with high yield. The structures of the products were supported by FTIR, PMR and mass spectral data