A Solvent Free Green Protocol for Synthesis of 5-Arylidine Barbituric Acid Derivatives

Uttam BM

Abstract

A green approach to the condensation reaction of aromatic aldehydes and barbituric acid has been described using sodium acetate as a catalyst with grinding at room temperature without using solvent. Short reaction time, higher yields and clean reaction makes this protocol an attractive alternative to the existing methods.

Relevant Publications in Organic Chemistry : An Indian Journal