A solvent free synthesis of coumarins via Pechmann condensation using PMA: Silica supported BF3:OEt2 catalyst

Research Article

Omprakash S. Chavan, S. B. Cha

Abstract

Synthesis of substituted Coumarins from phenol and β-ketoester(Ethyl Acetoacetate) via Pechmann condensation using heterogeneous catalyst Phosphomolybdic Acid (PMA):Silica supported BF3:OEt2 under solvent free condition. This one required low reaction time, mild reaction condition, at room temperature and easy workup with excellent yield of the product.

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