A study of extract optimization and effect of metal ions on antibacterial properties of Argemone mexicana

Amit Pandey* and Vikas Karanwa

Abstract

Argemone mexicana has influenced culture aesthetically, economically, medically & spiritually. Ethanolic and Methanolic extract of Antibacterial activity of leaf & fruit (Seed) of Argemone mexicana was evaluated against some pathogenic bacteria- Pseudomonas aeruginosa & E.coli (Gram negative) and one was Staphylococcus aureus (Gram positive). Ethanolic extract of Argemone mexicana was showing best result in seed sample with MIC value 0.00023 mg/ml. After addition of some metal ions (zinc, calcium, iron, magnesium & lead), the antibacterial activity was increased in sample along with zinc ion (10%) which was shown that some metal ion can increase the antibacterial property.