An Efficient and Operationally Simple Synthesis of Some New Chalcones by Using Grinding Technique

S Zangade, S Mokle, A Vibhu

Abstract

An efficient and operationally simple reaction is shown between substituted 2-acetyl-1-naphthol/2-acetyl-1-naphthol and different substituted benzaldehydes in presence of base afford chalcones in quantitative yield using grindstone technique. Mild reaction condition, no need of catalyst, non-hazardous and environmentally safer, giving excellent yield in short reaction time, are notable advantages of this method.