An Efficient One Pot Synthesis of Pyrazolo [3,4-b] pyrido[1,2-a] pyrimidine and its Antimicrobial Evaluation

Sambhaji P. Vartale, Nagesh D.

Abstract

Pyrazolo pyrimido pyrimidine (4a-j) were prepared by the reaction of compound 3-cyano-4-imino-7-methyl-2-(methylthio)-4Hpyrido [1,2-a] pyrimidine (3) with hydrazine hydrate, phenyl hydrazine, 2-hydrazino benzothiazole & 6-substuited hydrazine benzothiazole in N,N-dimethyl formamide (DMF) and catalytic amount of anhydrous potassium carbonate. All these newly synthesized compounds were characterized by elemental analysis and spectral data