Research Article
S. Gopalakrishnan, V. K. Meena
Abstract
Methanolic extract of the simple ascidian, Phallusia nigra Sav. was subjected to anaesthetic activity by intracutaneous wheal method. The extract, when administered at a dose of 10% and 15% caused highly significant anaesthetic activity when compared to the standard drug xylocaine (1%). The mean sleeping time and percentage relaxtion of muscle was also highly significant in the extract treated groups compared to the standard drug, Aminobarbitone