Anti-Inflammatory and Antioxidant Activity of Some Acid Chloride Derivatives of 2-Amino-N- (3-Chlorophenyl)-5, 6-Dihydro-4H-Cyclopenta [b] Thiophen-3-Carboxamide

K. Pavan Kumar, K. Anupama and

Abstract

2-Amino-N- (3-chlorophenyl)-5, 6-dihydro-4H-cyclopenta [b] thiophene-3-carboxamide was synthesized by application of Gewald reaction. The acid chloride derivatives were screened for in vitro anti-inflammatory and antioxidant activity comparable to that of ibuprofen and ascorbic acid, respectively.