Anti-microbial and Anti-Inflammatory Activity of Bioactive Components of Pavonia odorata Wild

Rayar A., Aeganathan R., Ilaya

Abstract

Root extracts of Pavonia odorata has to investigate the bioactive compounds using GC-MS analysis. It revealed the existence of 9 compounds. The present investigation was undertaken by comparative study of antimicrobial and anti-inflammatory activity between chloroform, ethyl acetate and methanolic extracts. The chloroform and ethyl acetate extract has excellent activity against Staphylococcus aureus (24 ± 0.69 & 22 ± 1.38 mm) and Candida albicans (19 ± 0.24 & 16 ± 1.02 mm). The anti-inflammatory activity of root extracts, Carrageenan-induced rat paw edema has frequently used to assess the anti-inflammatory effects of natural products. Chloroform extract has higher activity than ethyl acetate extract. It may be due to the presence of bioactive components.

Relevant Publications in American Journal of Phytomedicine and Clinical Therapeutics