Antioxidant, Antiinflammatory And Antihistaminic Activities of Some Phenylpyrazolo Benzothiazolo Quinoxaline Derivatives

Sridevi CH, Balaji K, Naidu A

Abstract

Pharmacologically, phenyl pyrazolo benzothiazolo quinoxaline derivatives are known to exhibit important biological activities like antimicrobial1, antitubercular2, anti-inflammatory3, antioxidant4, antihistamic5, antidepressant, hypoglycemic, hypotensive, anticarcenogenic activities6 etc. In view of these reports, the synthesis of title compounds has been undertaken in the present note and their antioxidant, anti-inflammatory and antihistaminic properties are reported. The structure of chalcones and phenyl pyrazolo benzothiazolo quinoxaline derivatives were confirmed by M. P, TLC and spectral data.