Research Article
Syed Ayaz Ali, Saudagar Mujahi
Abstract
To evaluate the anti-ulcer activity of Caesalpinia pulcherrima on ethanol induced gastric lesion in albino rat. Gastric lesions were induced in rats by oral administration of ethanol 80% Ethanol (1 ml, p.o).The anti-ulcer activity of ethanolic extract of flowers of Caesalpinia pulcherrima (CPFE) was compared with standard drug (Famotidine). The parameter studied were ulcer index, pH, gastric juice volume, total acidity, tissue glutathione, and total protein against ethanol induced gastric ulcer in rats. The results obtained from the present study have shown that flower of Caesalpinia pulcherrima possesses antiulcer effect on ethanol induced ulcer where, a decrease in ulcer index, total acidity, total volume of gastric secretion and increase in total protein, glutathione content and pH of gastric secretion when compared with toxic was observed. The present study suggests the anti-ulcerative activity of ethanolic extract of flower of Caesalpinia pulcherrima.