Assessing missed opportunities for the prevention of early onset neonatal infection by group B streptococcus

Joana Ferreira Carvalho

Abstract

Group B Streptococcus (GBS) is the leading cause of early onset neonatal infection (EONI). In November/2003 our Department established a protocol aimed at preventing this infection, based on the recommendations set forth by the Centers for Disease Control and Prevention in of 2002. Purpose: To assess the missed opportunities for prevention of EONI by GBS. Methods: Culture proven EONI by GBS cases occurring between 2004 and May/2010 were identified retrospectively. Data concerning risk factors of the infection, intrapartum procedures and clinical outcome of newborns were collected and analyzed. Results: There were 15 cases of EONI by GBS over the study period (0.81/1000 live-births), with no deaths recorded. In 10 cases pregnant women were not subject to antenatal screening. Among the 5 women screened, the corresponding result was negative in 3 of them and positive in the other 2 and these 2 women did not made intrapartum antibioprophylaxis. We could have been prevented 6 cases of EONI. Conclusio: Better GBS prevention is required in our department, as increasing the implementation of antenatal screening and improving compliance with the administration of intrapartum antibioprophylaxis.

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