Association of Serum Adiponectin with Age, BMI and Other Breast Cancer Biomarkers

Research Article

Rabindra Nath Das and Youngjo

Abstract

Throughout the world, the most commonly observed cancer in women is breast cancer. Low serum adiponectin levels are positively associated with breast cancer, so it is treated as a breast cancer biomarker. The report focuses the association of adiponectin with age, body mass index, and other breast cancer biomarkers. It is derived herein that mean adiponectin is negatively associated with Age (P=0.0006), Body mass index (BMI) (P<0.0001), Resistin (P=0.0237), while it is positively associated with interaction effects Age*BMI (P=0.0017) and BMI*Resistin (P=0.0615). Some partially significant effects such as Leptin (mean model) and Age (variance model) are also included in the model as confounder (known in Epidemiology). Adiponectin is higher for younger women with low body mass index and low resistin levels, and it is not associated with serum glucose and insulin levels.

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