Letter to Editor
Isabelle Leticia Zaboroski Sil
Abstract
The canonical Wnt pathway plays an important role in numerous cell processes, such as embryogenesis, cell proliferation, self-renewal of stem cells, myogenesis, and adipogenesis. This pathway is mediated by specific factors called Wnt proteins, which act as chemical mediators controlling the development of different types of cells. Wnt proteins are structurally different from other proteins, in that they have a fatty acid chain bound covalently at their N-terminal region. The Wnt pathway is regulated by another protein, beta-catenin (β-cat). It is known that β-cat activates the transcription of more than 60 different genes