Perspective Article
Bharthi R, Dhilleswara Rao
Abstract
ABSTRACT The discovery of embryonic and adult stem cells is one of the ground breaking findings, which offer new treatment options for various cardiovascular diseases. Embryonic stem cells can differentiated into multiple cell lineages in vitro such as cardiac myocytes when transplanted into the heart. Few recent studies showed that the infusion of bone marrow-determined cells has remarkable clinical significance and useful advantage. The phase I/II clinical studies have proved that the bone marrow derived mononuclear cells offer variety options; however, their clinical are limited. This review summarizes the role of CPCs in treatment of cardiovascular diseases, clinical opportunities, challenges in usage of CPCs in human models and the future prospective.