Review Article
Sandeep Nijhawan, Gopal Goyal
Abstract
Celiac disease (CD) is a systemic, immune-mediated disorder that primarily affect small intestine and triggered by dietary gluten in genetically susceptible individuals. Gluten is a water insoluble protein complex, which is found in wheat, rye and barley. A significant finding of celiac disease is villous atrophy of small intestine which leads to nutrient malabsorption and broad range of clinical manifestations.