Research Article
Gulam Qadir Bhat, Showkat Ali
Abstract
Objective: This study was undertaken to study the correlation between imprint cytology, crush smears and histopathology in endobronchial growths using fiberoptic bronchoscopy. Methods: The study was conducted in the Department of Internal Medicine and Pathology at Sher-i-Kashmir Institute of Medical Sciences. Eighty-one patients with clinical and radiological evidences of lung lesions were enrolled. From all patients five pieces of tissue were obtained during fiberoptic broncoscopy which revealed an endobronchial growth. From each bit of tissue an imprint and crush smear were prepared by imprinting the tissue on a clean surface of glass slide without compressing the tissue while as crush smear was made by gently crushing the tissue between two glass slides. The tissue specimens were then placed in formaldehyde solution for histological examination. Standard statistical methods were used to analyze the data (chi-square (χ2) analysis; a Fisher’s exact test was used to evaluate the data if more than 25% of the expected values were <5). The level of significance selected was P<0.05.