Research Article
Dinkar Mundhe , A. V. Chandewa
Abstract
The emergence of XDR & MDR tuberculosis have forced medicinal chemist to think out of the box to arrive at promising “Hit”. Here is the report which, suggest our attempt to discover a clubbed thiazolyl-triazole molecule that has shown potency almost comparable with isoniazid. Further evaluation with almost 25 XDR & MDR clinical isolates of tuberculosis suggest better profile of drug candidate than reference drug, isoniazid. The candidate is under further development status and is showing promising activity with lesser toxicity.