Case Report
Nosha Farhadfar, Amishi Des
Abstract
Post-Transfusion Purpura (PTP) is a rare, yet potentially fatal bleeding disorder characterized by severe thrombocytopenia, purpura and hemorrhage that occurs after transfusion of blood product. It is caused by alloimmunization against platelet antigens, anti-HPA-1a being the most frequent antibody. We report a rare case of PTP due to an even more unusual anti-HPA-5a alloantibody after platelet transfusion and discuss the clinical presentation, diagnosis and management of this life threatening condition