Docking Studies of few C-3 Substituted Azapteridines as Hepatitis C Virus RNA-Dependent RNA Polymerase inhibitors

Anil M. Manikrao, Niranjan S.

Abstract

Docking studies of few C-3 Substituted Azapteridines which act as Hepatitis C Virus RNADependent RNA Polymerase inhibitor was performed by using MOE 2009. The docking studies reveal that majority of the Azapteridine derivatives interacted with Hepatitis C Virus RNADependent RNA Polymerase through hydrogen bonding as well as hydrophobic interactions. The present analysis is useful in future drug design.