Does mRNA Stability Play a Role in Thyroid Cancer?

Bogusz Trojanowicz and Cuong H

Abstract

In the search for novel molecular markers for thyroid carcinoma, we found that both proteins involved in the regulation of mRNA stability, AUF1 and HuR, may play a particular role in the tumor progression. Functional, these proteins may bind and regulate the stability of mRNAs related to the cell cycle leading to uncontrolled growth and progression of tumor cells.

Relevant Publications in Journal of Clinical & Molecular Endocrinology