Case Report
Chetta M, Di-Matteo L, Russ
Abstract
Apparently balanced reciprocal translocations are a common type of chromosome rearrangements with an estimate incidence range from about 1 in 500 to 1 in 625 human newborns. Rearrangements were found both in clinically unaffected individuals and patients with phenotypic abnormalities. Most are inherited, but approximately one in five are de novo events and introduce a risk of abnormal phenotype in 6.1% of prenatal genetic counseling.