The study examined entrepreneurship development as a panacea for a depressed economy with particular reference to Metro-B Nigeria Limited Onitsha. The main objective of the study is to examine the need to cushion the adverse effect of depressed economy through entrepreneurship development in Nigeria. Related literatures were reviewed. The study adopted descriptive research method in which data generated through questionnaire and oral interview were analyzed. The hypotheses formulated in the study were testing chi-square statistical method. The study revealed that entrepreneurship development plays a key role in the process of economic development through employment creation, increase in investment and consumption of a nation thereby revamping the depressed economy.