Original Articles
Nikhil K Sachan,S. K. Ghoshand
Abstract
The microbeads were prepared by an industrially fea sible micro orifice ionotropic-getation method using glutinous rice starch from Assam Bora rice, and sodium alginate backbone with different crosslinking agents. The microbeads fabri cated through several preformulation trials were evaluated in reference to drug release, drug e xcipient compatibility and mucoadhesive potential. The effect of various formulation and pr ocessing parameters was studied by scanning electron photomicrographs taken before and after di ssolution. Photomicrographs provides the information about the surface texture, size, mechan istic properties, suitability of drying condition and mechanism of drug release from the prepared mic ro devices.