Food Refusal, Loss of Appetite, Chronic Fatigue and Depression due to Central Adrenal Insufficiency Presenting as Anorexia Nervosa in an Adolescent Girl

Martine KF Docx, Annik Simo

Abstract

The estimated prevalence of secondary and tertiary (central) adrenal insufficiency is 150-280 per million [1]. A lot of processes that involves the hypothalamus and which interferes with CorticotrophinReleasing Hormone (CRH) secretionare hypothalamic tumors, surgery, irradiation and autoimmune hypothalamic disease will result in central adrenal failure.