Research Article
Kambhampati A, Patil AP. and D
Abstract
This study analysed the genome of gram negative non-proteo infectious bacteria to find out the analogous proteins present in them, so that we can develop a drug that can act on the specific targets present in the maximum number of strains of these bacteria’s. Our main interest was in the Adhesins which with the help of softwares and databases helped in predicting the “target” domains. NCBI, ClustalW2, SPAAN, CDD and many other computational techniques and softwares were utilized for this study. We predicted the domains that can be used as potential targets in drug discovery. Out of the 900 adhesins, 786 proteins with either one of more than one domain and 114 proteins were without conserved region were predicted with the help of a database