Helicobacter Pylori Infection Induces Gastric Cancer and the Cancer/Testis Antigens Expression

Nobue Futawatari, Takashi Fuku

Abstract

Helicobacter pylori (HP) are known to induce gastritis, atrophy, intestinal metaplasia, dysplasia, and stomach malignancy. HP infection also induces cancer/testis antigens (CTAs) during or after gastric malignancy. This study aims to elucidate the relationship between HP and CTAs, especially melanoma antigen-A3 and Kitakyushu lung cancer antigen-1.