Alexander E. Berezin
Abstract
Diabetes Mellitus (DM) remains a leading cause of Cardiovascular (CV) mortality and morbidity worldwide. Recent studies have revealed that reduced number and weak function of Endothelial Progenitor Cells (EPCs) directly contribute in the impaired endothelial reparation in diabetics. Moreover, EPC dysfunction may worse functioning of vasculature and increase CV risk. There is evidence that restoring of EPCs number and functional ability may entail reducing DM-related complications and an improvement of CV outcomes. The aim of the editorial is summary of knowledge regarding EPCs dysfunction in diabetics.