Importance of Fibronectin for Clostridium perfringens Adhesion to Host Tissue

Yasuo Hitsumoto, Nozomu Matsun

Abstract

Clostridium perfringens, a Gram-positive, spore-forming, obligate anaerobe, is the cause of gas gangrene and food poisoning. Colonization of the host requires adhesion of bacterial cells to injured tissue. We review here recent results regarding the role of fibronectin in the interaction of C. perfringens cells with host collagens.