Research Article
Ajibade Oluwatosin1*, Oladipo
Abstract
Fifty clinical isolates of Pseudomonas aeruginosa were obtained from both in and out-patients of selected hospitals in Oyo State, Nigeria using standard procedure. Presumptive identification of the isolates was carried out using standard biochemical tests. according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. The antibiotics used in the study includes: Ciprotab, Colistin-sulphate, Meropenem, Ceftriaxone and Cefepime. 50 clinical isolates of Pseudomonas aeruginosa obtained, consisting of 48% male isolates and 52%female isolates. The percentage ratio of in-patient and out-patient examined were 32% and 68%. The percentage distribution of the administration class for medical and surgical was 34% and 66% respectively. The highest incidence of Pseudomonas aeruginosa was from patients that have undergone caesarean section (28%). Highest susceptibility was observed in Ciprotab (82%) Meropenem (64%) and Ceftraxone (46%). Highest number of resistance was observed against Cefepime and Colistin Sulphate while less than 5% were resistant to Ciprotab and Meropenem. Meropenemand ciprotab were the two classes of drugs that showed highest activity against Pseudomonas aeruginosa. Commonly used antibiotics must be continuously examined for its efficacy. There is therefore a need for consistent screening of microorganisms implicated with various infections characterization of their antimicrobial susceptibility pattern which will serve as a guide to clinicians in the selection of appropriate antimicrobial drug for empirical treatment of infections.