Indion 860 catalyzed green synthesis of 2,6-unsubstituted dihydropyridines in PEG-400

Surendra Bose Bathula,K.Mukkan

Abstract

Indion 860 mediated MCR of anilines, aldehydes and ethyl-3,3- diethoxypropionate in PEG-400 afforded 2,6-unsubstituted dihydropyridines depending on the nature of anilines employed. A variety of dihydropyridines were prepared by using this green methodology in good yields and Indion 860 was found to be an inexpensive and reusable catalyst.