Investigation of in vitro anthelmintic activity of Cassia auriculata leaves

Sushma Kainsa, Praveen Kumar a

Abstract

Four extracts viz. Petroleum ether, Ethyl acetate, Ethanol and Aqueous extracts of Cassia auriculata leaves were investigated for the anthelmintic activity against earthworms [Eisenia foetida]. Three concentrations [20, 40, 60 mg/ml] of each extract were studied which included the determination of time of paralysis and time of death of earthworms. Piperazine citrate [10 mg/ml] was used as standard drug and distilled water containing 2% Tween 80 was used as control. All the extracts exhibited dose dependent anthelmintic activity. The decreasing order of activity of extracts was ethyl acetate, ethanol, petroleum ether and aqueous extracts.

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