Invitro antioxidant impact of tocotrienols on lipoprotien lipid peroxidation in young smokers

Research Article

Amir Khan, Fouzia Ishaq and De

Abstract

Smoking is responsible for the death of about 3.5 million subjects every year, 10,000 deaths per day. Smoking is a major risk factor for cancer, heart and lung diseases. The smoke is able to cause tissue oxidative damage at various levels. Tocotrienols are the primary form of Vitamin E. The identification of γ-tocotrienol as a choliesterogenesis inhibitory factor derived from barley represents a landmark early discovery highlighting the unique significance of tocotrienols in health and diseases. In this study we investigated the efficacy of antioxidative power of tocotrienols by analyzing all the parameters in plasma, VLDL-C, LDL-C, HDL-C, HDL2-C, HDL3-C, LDL-Protein, HDLProtein, VLDL-Protein, MDA, CD and in vitro oxidizability of LDL in absence and presence of Tocotrienols.

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