Ionic Liquid Mediated Rapid Synthesis of 3-Subtituted Pyrazoles

Chandrashekhar G Devkate, Khan

Abstract

A simple, highly efficient and environmentally friendly method for the synthesis 3-substituted pyrazoles by one pot condensation reaction of substituted cinnamaldehydes and tosylhydrazine in ionic liquid, 1-Butyl-3-methylimidazolium tetrafluoroborate. This method was developed by screening of different imidazolium-based ionic liquids. The reaction system exhibited tolerance with various functional groups and gives good to excellent yields.

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