Lipoprotein Glomerulopathy: Molecular Characterization of Three Italian Patients and Literature Survey

Antonio Pasquariello, Livia

Abstract

Lipoprotein Glomerulopathy: Molecular Characterization of Three Italian Patients and Literature Survey Lipoprotein glomerulopathy (LPG) is a rare kidney disease, mainly reported in Asian subjects, linked with rare APOE gene mutations resulting in a structurally abnormal Apolipoprotein E (ApoE), the plasma accumulation of lipoprotein remnants and the formation of lipid thrombi in glomerular capillaries. This study reports the molecular characterization of three unrelated Italian patients with long standing LPG.