Case Report
Santiago Mercadal, Fina Climen
Abstract
Background: primary central nervous Hodgkin Lymphoma is a very rare event that occurs in less than 0.2% of cases, most of them in immunosuppressed patients.Case presentation: We describe a 59 year-old man with a 20 year history of ulcerative colitis treated with azathioprine during 6 years who developed a primary central nervous system Hodgkin Lymphoma. Inmunohistochemical study was positive for Epstein-Barr virus showing a type II latency pattern. The patient was treated with chemotherapy regimen consisting on high dose methotrexate and cytosine arabinoside achieving complete remission that remains more than five years after diagnosis.Conclusions: To the best of our knowledge we present the first case in the literature of a primary central nervous system hodgkin lymphoma in a immunossupressed patient due to azathioprine with a long remission after chemotherapy alone.