Metal Complexes with the Fluoroquinolone Antibacterial Agent Norfloxacin : Synthesis, Structure and Bioactivity

Ajay Kumar and Danveer Singh Y

Abstract

Three novel complexes of fluro quinolones antibacterial agent norfloxacin (abbreviated as Nor), [M(Nor)2(H2O)2]Cl3.6H2O, (M = Fe, Co) and [Zn(Nor)2]Cl2.7H2O, have been prepared. The compounds were characterized by IR, UV-Vis, NMR spectra, molar conductivity and elemental analyses. In all of the complexes, the ligand Nor was coordinated through two carboxyl oxygen atoms. Octahedral and tetrahedron geometries have been proposed for Fe (III)-, Co (II)-complexes and Zn (II)-complex, respectively.