Metformin as Adjunctive Therapy in Acanthosis Nigricans Treatment: Two Arms Single Blinded Clinical Trial

Alkhayrat A, Alshamrani N,

Abstract

Acanthosis nigricans (AN) is a skin disorder that is characterized by dark discolorations with velvety texture. The safety and efficacy  of using metformin as adjunctive therapy to the topical agents in AN remain uncertain. Our primary objective is to quantify AN severity improvement.