Microwave Assisted Rapid Synthesis of 3, 4-Dihydropyrimidine-2-(1H)-Ones/Thiones Using LSA as a Catalyst under Solvent Free Conditions

Sadhana N. Chamle, Manjusha V.

Abstract

Lignin Sulphonic Acid (LSA) was found to be an efficient catalyst for the synthesis of 3, 4- dihydropyrimidin-2-(1H)-ones/thiones from the multicomponent condensation reaction of aromatic aldehyde, ethyl acetoacetate and urea / thiourea in solventfree condition on microwave at 180 W.