Microwave assisted synthesis of 6-methyl-1,2,3,4-tetrahydro-N-aryl-2-oxo-4-arylpyrimidine-5-carboxamide and 3, 4-dihydropyrimidin-2(1H)-ones under solvent free conditions

I. T. Phucho, S. Tumtin, A. No

Abstract

6-Methyl-1,2,3,4-tetrahydro-N-aryl-2-oxo-4-arylpyri midine-5-carboxamide and 5-unsubstituted 3, 4-dihydropyrimidin-2(1H)-ones have been synthesi sed from three component cyclocondensation of N-aryl-3-oxobutanamide/acetoph enone, aldehyde and urea /thiourea in presence of PTSA under solvent free microwave irrad iation