Microwave Mediated Mild, One-Pot Synthesis of Novel Pyrazinobenzimidazole Derivatives and their Anticancer Properties

Shalini Yadav and P. K. Sharma

Abstract

Some novel pyrazinobenzimidazole derivatives were synthesized via a microwave-assisted cycloaddition and cyclocondensation heterocyclic reactions using I-(2-aryl-2-oxoethyl)-2-aryloylimidazole as a key intermediate compound and tested their anticancer properties on Leukemia all lines. All the prepared compounds were characterized by FTIR, IH NMR and mass spectral analysis.