Mini Review: Potential Role of Hormones in the Tumors of Neurofibromatosis Type-1

Mauro Geller, Lisa Oliveira

Abstract

Neurofibromatosis type 1 is an autosomal dominant neurocutaneous disorder caused by mutations in the NF1 gene, and presents a very broad spectrum of clinical manifestations and severity, including dermal and plexiform neurofibromas. In this mini review we briefly address the findings present in the literature related to hormone receptors within these tumor types.