Molecular interaction study of substituted azomethine drugs refractometrically

Research Article

A. V. Kawalkar and M. P. Wadek

Abstract

The densities and refractive index of substituted azomethine drugs of different concentration in 70% (DMF+water) binary mixture has been studied. The experimental data shows that the molar refraction and polarizability constant of substituted azomethine drugs decreases with decrease in concentration of ligand in 70%(DMF+ water) solvent and increases with increase in percent of organic solvent, over a constant ligand concentration. The data helps to predict the solute-solute, solute-solvent and solvent-solvent interaction in the system.

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