Multicomponent catalytic synthesis of 1,2,3-triazoles by regio specific copper(I)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides

Alireza Salimi Beni*, Saeideh

Abstract

An efficient, facile, and practical liquid-phase combinatorial synthesis of various 1,2,3-triazoles was synthesizedfrom phenylacetylene, sodium azide and alkyl halide via a one-step process in the presence of a catalytic amount of a copper-salen complex in the water.