Research Article
Clotaire Danho Nanho1, Dieu
Abstract
Background: No studies have been conducted concerning Multiple Myeloma (MM) associated Human Immunodeficiency Virus (HIV) in Côte d'Ivoire. Aim: To describe the peculiarities of association MM-HIV. Materials and methods: We conducted a retrospective and descriptive study with duration of 8 years, from January 2009 to December 2017 in Abidjan. We included the case of MM with HIV serology positive. 10 patients among 101 cases of MM were infected by HIV, prevalence of 9.9%. Results: There were 6 mens and 4 females. The average age was 53 years with extremes 31 and 75 years. Clinical signs were bone pain (10 cases), anemia (10 cases), pathological fractures (6 cases) and tumor syndrome (3 cases). Biologically, 8 patients had a hemoglobin level<6 d/dl, 6 had a hypercalcemia and 3 had renal failure. Radiological signs noted a Geode in all patients which 5 were multiple. 7 patients had been stadified ISS III. Therapeutic responses noted Complete Response (one case), Very Good Partial Response (two cases), and Partial Response (5 cases). Conclusion: MM associated HIV in Côte d'Ivoire is most to young people with severe manifestations. The treatment seems good with the use of conventional chemotherapy.