Review Article
Niwat Polnikorn
Abstract
Melasma is one of the most common aesthetic problems in Asians and is one of the most difficult conditions to be treated. In the past result after laser treatment was usually believe to be unpredictable. This believes was based on anecdotal reports with variable laser parameters. In order to get better and long lasting result, we need to understand biology of melanin synthesis, pathogenesis of melasma, laser / light tissue reaction, sun screen and effect of whitening agents.