New Approaches to Simulation of Enzymatic Reactions: Mimetic Catalysis

Tofik M Nagiev


The area between enzymatic and chemical catalysis, related to simulation of biochemical processes by their basic parameters, is accepted as mimetic catalysis. The main aspect of mimetic catalyst is the diversity of enzyme and biomimetic function processes, which principally distinguishes the mimetic model from the traditional full simulation. Basing on the analysis of conformities and diversities of enzymatic and chemical catalysis the general aspects of mimetic catalysis are discussed. Idealized model of biomimetic catalyst and the exclusive role of the membrane in its structural organization are considered. The most important achievements in the branch of catalysis are shown, in particular, new approaches to synthesis and study of biomimetic catalase, peroxidase and monoxides reactions.

Relevant Publications in Journal of Pharmaceutical Chemistry & Chemical Science